| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADP13996.1 | guaA | AXYL_00638 | AXYL_03734 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.687 |
| ADP13996.1 | queE | AXYL_00638 | AXYL_03511 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Radical SAM superfamily protein 3; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.917 |
| ADP16236.1 | nrdD | AXYL_02916 | AXYL_02917 | Anaerobic ribonucleoside triphosphate reductase domain protein. | Anaerobic ribonucleoside-triphosphate reductase. | 0.926 |
| ADP16236.1 | queE | AXYL_02916 | AXYL_03511 | Anaerobic ribonucleoside triphosphate reductase domain protein. | Radical SAM superfamily protein 3; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.775 |
| ADP16830.1 | queD | AXYL_03510 | AXYL_03512 | peptidyl-tRNA hydrolase domain protein. | Queuosine biosynthesis protein QueD. | 0.514 |
| ADP16830.1 | queE | AXYL_03510 | AXYL_03511 | peptidyl-tRNA hydrolase domain protein. | Radical SAM superfamily protein 3; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.588 |
| folE2 | guaA | AXYL_02895 | AXYL_03734 | GTP cyclohydrolase 2. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.465 |
| folE2 | nrdD | AXYL_02895 | AXYL_02917 | GTP cyclohydrolase 2. | Anaerobic ribonucleoside-triphosphate reductase. | 0.806 |
| folE2 | queC | AXYL_02895 | AXYL_05942 | GTP cyclohydrolase 2. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.446 |
| folE2 | queD | AXYL_02895 | AXYL_03512 | GTP cyclohydrolase 2. | Queuosine biosynthesis protein QueD. | 0.972 |
| folE2 | queE | AXYL_02895 | AXYL_03511 | GTP cyclohydrolase 2. | Radical SAM superfamily protein 3; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.620 |
| folE2 | queF | AXYL_02895 | AXYL_04373 | GTP cyclohydrolase 2. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.538 |
| guaA | ADP13996.1 | AXYL_03734 | AXYL_00638 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.687 |
| guaA | folE2 | AXYL_03734 | AXYL_02895 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase 2. | 0.465 |
| guaA | queC | AXYL_03734 | AXYL_05942 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.442 |
| guaA | queD | AXYL_03734 | AXYL_03512 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Queuosine biosynthesis protein QueD. | 0.487 |
| guaA | queE | AXYL_03734 | AXYL_03511 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Radical SAM superfamily protein 3; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.583 |
| guaA | queF | AXYL_03734 | AXYL_04373 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.633 |
| nrdD | ADP16236.1 | AXYL_02917 | AXYL_02916 | Anaerobic ribonucleoside-triphosphate reductase. | Anaerobic ribonucleoside triphosphate reductase domain protein. | 0.926 |
| nrdD | folE2 | AXYL_02917 | AXYL_02895 | Anaerobic ribonucleoside-triphosphate reductase. | GTP cyclohydrolase 2. | 0.806 |