STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADP17478.1Dehydratase family protein 5; Belongs to the IlvD/Edd family. (581 aa)    
Predicted Functional Partners:
ilvB1
Acetolactate synthase, large subunit, biosynthetic type 1.
 
 
 0.769
ilvB3
Acetolactate synthase, large subunit, biosynthetic type 3.
 
 
 0.760
atrC
Acetolactate synthase catalytic subunit; Belongs to the TPP enzyme family.
 
 
 0.725
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.712
ilvN
Acetolactate synthase, small subunit.
 
 
 0.685
ADP16407.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 4; Belongs to the TPP enzyme family.
 
 
 0.667
ADP18002.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 7; Belongs to the TPP enzyme family.
 
 
 0.666
ADP16412.1
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 5; Belongs to the TPP enzyme family.
 
 
 0.641
ADP17479.1
malate/L-lactate dehydrogenase family protein 4; Belongs to the LDH2/MDH2 oxidoreductase family.
       0.637
ADP17477.1
Extra-cytoplasmic solute receptor family protein 98.
       0.636
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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