STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
acnA2Aconitate hydratase 2; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (901 aa)    
Predicted Functional Partners:
icd1
Isocitrate dehydrogenase, NADP-dependent 1.
 
 0.984
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 0.979
prpF
AcnD-accessory protein PrpF.
 
 
 0.976
gltA
Citrate (Si)-synthase; Belongs to the citrate synthase family.
 
 0.943
prpB1
Methylisocitrate lyase 1; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 0.934
ADP13622.1
Citrate synthase 1.
  
 0.931
ADP13868.1
Citrate synthase 2.
  
 0.931
prpD
2-methylcitrate dehydratase.
  
 
 0.921
icd2
Isocitrate dehydrogenase, NADP-dependent 2; Belongs to the monomeric-type IDH family.
  
 
 0.920
aceA
Isocitrate lyase.
   
 
 0.917
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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