STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cysESerine O-acetyltransferase. (315 aa)    
Predicted Functional Partners:
cysM
Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.992
sdaA
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.918
ADP14052.1
Pyridoxal-phosphate dependent enzyme family protein 2.
    
 0.908
hom
Homoserine dehydrogenase.
 
  
 0.863
serB1
Phosphoserine phosphatase SerB 1.
    
 0.840
serB2
Phosphoserine phosphatase SerB 2.
    
 0.840
glyA1
Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.828
thrB
Homoserine kinase; Belongs to the pseudomonas-type ThrB family.
 
  
  0.828
glyA2
Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.828
ADP13372.1
Pyridoxal-phosphate dependent enzyme family protein 1.
    
 0.816
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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