STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADP17929.13-hydroxy-3-methylglutaryl-CoA lyase 3; Belongs to the alpha-IPM synthase/homocitrate synthase family. (312 aa)    
Predicted Functional Partners:
ADP15727.1
enoyl-CoA hydratase/isomerase family protein 7; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.958
ADP18453.1
enoyl-CoA hydratase/isomerase family protein 30.
 
 0.950
ADP19201.1
enoyl-CoA hydratase/isomerase family protein 33.
  
 
 0.937
scoA1
succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A 1.
  
 
 0.926
ADP14934.1
3-oxoacid CoA-transferase, B subunit 1.
  
 
 0.925
bdhA1
3-hydroxybutyrate dehydrogenase 1.
   
 
 0.917
bdhA2
3-hydroxybutyrate dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.917
bdhA4
3-hydroxybutyrate dehydrogenase 4; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.917
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.836
sucD
succinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.825
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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