Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADP18234.1Peptidase, M50 family. (717 aa)    
Predicted Functional Partners:
ADP18235.1
GAF domain protein 1.
 
     0.955
ADP18236.1
Hemolysin-type calcium-binding repeat family protein 4.
 
   
 0.939
ADP18232.1
Secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.890
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.836
secA2
Protein translocase subunit SecA 2; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
     
 0.797
ADP18239.1
SapC family protein.
 
     0.644
ADP18237.1
Type I secretion outer membrane protein, TolC family protein 3.
  
 
 0.625
ADP18238.1
Hypothetical protein.
       0.515
cusA
Cation efflux system protein CusA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.426
czcA
Cation efflux system protein CZCA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.426
Your Current Organism:
Achromobacter xylosoxidans
NCBI taxonomy Id: 762376
Other names: A. xylosoxidans A8, Achromobacter xylosoxidans A8, Achromobacter xylosoxidans str. A8, Achromobacter xylosoxidans strain A8
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