| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADY51560.1 | ADY52521.1 | Pedsa_0989 | Pedsa_1968 | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.791 |
| ADY51560.1 | ADY52641.1 | Pedsa_0989 | Pedsa_2089 | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | Carboxylyase-related protein; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: phe:Phep_2913 carboxylyase-related protein; PFAM: Carboxylyase-related protein; SPTR: Putative uncharacterized protein; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | 0.770 |
| ADY51560.1 | mqnA | Pedsa_0989 | Pedsa_1151 | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.943 |
| ADY51560.1 | mqnB | Pedsa_0989 | Pedsa_2886 | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.978 |
| ADY51560.1 | mqnD | Pedsa_0989 | Pedsa_2887 | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.980 |
| ADY51560.1 | ubiX | Pedsa_0989 | Pedsa_0923 | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.750 |
| ADY52521.1 | ADY51560.1 | Pedsa_1968 | Pedsa_0989 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | 0.791 |
| ADY52521.1 | ADY52522.1 | Pedsa_1968 | Pedsa_1969 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Oligoendopeptidase, M3 family; COGs: COG1164 Oligoendopeptidase F; InterPro IPR011976: IPR 001567; KEGG: phe:Phep_0974 oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; SPTR: Oligoendopeptidase F; TIGRFAM: oligoendopeptidase, M3 family; PFAM: Peptidase family M3; TIGRFAM: oligoendopeptidase, M3 family. | 0.841 |
| ADY52521.1 | ADY52641.1 | Pedsa_1968 | Pedsa_2089 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Carboxylyase-related protein; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: phe:Phep_2913 carboxylyase-related protein; PFAM: Carboxylyase-related protein; SPTR: Putative uncharacterized protein; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | 0.980 |
| ADY52521.1 | ADY54355.1 | Pedsa_1968 | Pedsa_3826 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: phe:Phep_0545 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Octaprenyl-diphosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.853 |
| ADY52521.1 | engB | Pedsa_1968 | Pedsa_1967 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.721 |
| ADY52521.1 | mqnA | Pedsa_1968 | Pedsa_1151 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.810 |
| ADY52521.1 | mqnB | Pedsa_1968 | Pedsa_2886 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.787 |
| ADY52521.1 | mqnD | Pedsa_1968 | Pedsa_2887 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.803 |
| ADY52521.1 | mqnE | Pedsa_1968 | Pedsa_1153 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.791 |
| ADY52521.1 | ubiX | Pedsa_1968 | Pedsa_0923 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.980 |
| ADY52522.1 | ADY52521.1 | Pedsa_1969 | Pedsa_1968 | Oligoendopeptidase, M3 family; COGs: COG1164 Oligoendopeptidase F; InterPro IPR011976: IPR 001567; KEGG: phe:Phep_0974 oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; SPTR: Oligoendopeptidase F; TIGRFAM: oligoendopeptidase, M3 family; PFAM: Peptidase family M3; TIGRFAM: oligoendopeptidase, M3 family. | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.841 |
| ADY52522.1 | engB | Pedsa_1969 | Pedsa_1967 | Oligoendopeptidase, M3 family; COGs: COG1164 Oligoendopeptidase F; InterPro IPR011976: IPR 001567; KEGG: phe:Phep_0974 oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; SPTR: Oligoendopeptidase F; TIGRFAM: oligoendopeptidase, M3 family; PFAM: Peptidase family M3; TIGRFAM: oligoendopeptidase, M3 family. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.646 |
| ADY52641.1 | ADY51560.1 | Pedsa_2089 | Pedsa_0989 | Carboxylyase-related protein; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: phe:Phep_2913 carboxylyase-related protein; PFAM: Carboxylyase-related protein; SPTR: Putative uncharacterized protein; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR005244: IPR 020050: IPR 006638: IPR 007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | 0.770 |
| ADY52641.1 | ADY52521.1 | Pedsa_2089 | Pedsa_1968 | Carboxylyase-related protein; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: phe:Phep_2913 carboxylyase-related protein; PFAM: Carboxylyase-related protein; SPTR: Putative uncharacterized protein; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR 000537; KEGG: phe:Phep_0975 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.980 |