STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY53678.1Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterPro IPR004808: IPR 000097: IPR 005135: IPR 020847: IPR 020848; KEGG: phe:Phep_4271 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). (255 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.968
ADY52085.1
Endonuclease/exonuclease/phosphatase; COGs: COG0708 Exonuclease III; InterPro IPR005135; KEGG: phe:Phep_1385 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family.
     
  0.900
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.795
ADY54303.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.783
ADY53666.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.748
ADY53677.1
COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: phe:Phep_4270 peptidyl-prolyl cis-trans isomerase cyclophilin type; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; SPTR: Peptidyl-prolyl cis-trans isomerase; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
  
 
  0.722
ADY51003.1
InterPro IPR002114: IPR 014127; KEGG: phe:Phep_2907 hypothetical protein; PFAM: Conserved hypothetical protein CHP02757; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2400); TIGRFAM: conserved hypothetical protein TIGR02757.
  
 0.713
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.705
ADY52657.1
PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR002054: IPR 003141: IPR 004013; KEGG: phe:Phep_3075 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; DNA polymerase X; SPTR: PHP domain protein; manually curated.
   
 0.696
ADY51628.1
DNA ligase D; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR012310: IPR 014144: IPR 014146: IPR 014143: IPR 014145: IPR 012309: IPR 002755; KEGG: cpi:Cpin_0998 DNA ligase D; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit; SPTR: DNA ligase D; TIGRFAM: DNA ligase D; DNA polymerase LigD, ligase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domai [...]
  
 
 0.668
Your Current Organism:
Pseudopedobacter saltans
NCBI taxonomy Id: 762903
Other names: P. saltans DSM 12145, Pedobacter saltans DSM 12145, Pedobacter saltans LMG 10337, Pedobacter saltans str. DSM 12145, Pedobacter saltans strain DSM 12145, Pseudopedobacter saltans DSM 12145
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