STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
derRibosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (433 aa)    
Predicted Functional Partners:
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR 011994; KEGG: phe:Phep_1190 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
 0.988
gpsA
COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR006168: IPR 011128: IPR 006109; KEGG: phe:Phep_0664 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; PRIAM: Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); SPTR: Glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.923
ADY53990.1
RNA-binding S4 domain protein; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR018496: IPR 002942: IPR 000748: IPR 006145; KEGG: phe:Phep_0498 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.866
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
   
0.806
ADY53445.1
GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterPro IPR000795: IPR 004161: IPR 000640: IPR 005225: IPR 006298; KEGG: phe:Phep_4050 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding elongation factor; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-bind [...]
  
  
 0.805
ADY51464.1
Hypothetical protein; COGs: COG0358 DNA primase; InterPro IPR002694; KEGG: cph:Cpha266_2065 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: CHC2 zinc finger.
  
  
 0.787
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.787
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.755
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
  
 0.736
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
  
 0.723
Your Current Organism:
Pseudopedobacter saltans
NCBI taxonomy Id: 762903
Other names: P. saltans DSM 12145, Pedobacter saltans DSM 12145, Pedobacter saltans LMG 10337, Pedobacter saltans str. DSM 12145, Pedobacter saltans strain DSM 12145, Pseudopedobacter saltans DSM 12145
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