STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY54042.1COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020613: IPR 002155: IPR 020616: IPR 020617; KEGG: fps:FP1586 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)    
Predicted Functional Partners:
ADY53136.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR 006108: IPR 001753; KEGG: phe:Phep_3724 3-hydroxyacyl-CoA dehydrogenase NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; SPTR: 4-enzyme protein: 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
 0.999
ADY53325.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR 001753; KEGG: fjo:Fjoh_0936 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.987
ADY54117.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR 001753; KEGG: phe:Phep_0225 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.985
ADY50859.1
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.954
ADY51216.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR 019810: IPR 010953; KEGG: phe:Phep_2053 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
 0.939
ADY53844.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.934
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.930
ADY51960.1
Succinate CoA transferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702: IPR 017821; KEGG: bba:Bd1620 acetyl-CoA hydrolase/transferase family protein; PFAM: acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; SPTR: Acetyl-CoA hydrolase/transferase family protein; TIGRFAM: succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases.
  
 
 0.921
ADY53138.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155: IPR 020616: IPR 020617: IPR 020615: IPR 020610: IPR 020613; KEGG: phe:Phep_3723 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.918
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
   
 
 0.913
Your Current Organism:
Pseudopedobacter saltans
NCBI taxonomy Id: 762903
Other names: P. saltans DSM 12145, Pedobacter saltans DSM 12145, Pedobacter saltans LMG 10337, Pedobacter saltans str. DSM 12145, Pedobacter saltans strain DSM 12145, Pseudopedobacter saltans DSM 12145
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.