STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGF58405.1OmpA family protein; KEGG: sli:Slin_0746 3.5e-05 V-type H(+)-translocating pyrophosphatase K01507. (384 aa)    
Predicted Functional Partners:
EGF58404.1
Hypothetical protein.
      0.797
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.612
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.595
rplY
Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
   0.490
rpmI
Ribosomal protein L35; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL35 family.
  
   0.480
rpmB
Ribosomal protein L28; KEGG: apb:SAR116_1905 1.5e-08 LSU ribosomal protein L28P K02902; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL28 family.
  
 
   0.448
EGF55472.1
Ribosomal protein S3; KEGG: apb:SAR116_2397 1.3e-57 ribosomal protein S3 K02982; Psort location: Cytoplasmic, score: 9.97; Belongs to the universal ribosomal protein uS3 family.
  
   0.439
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
   0.437
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
   0.408
rpsB
Ribosomal protein S2; KEGG: apb:SAR116_0519 2.0e-61 ribosomal protein S2 K02967; Psort location: Cytoplasmic, score: 9.97; Belongs to the universal ribosomal protein uS2 family.
   
   0.404
Your Current Organism:
Actinomyces sp. F0386
NCBI taxonomy Id: 762963
Other names: A. sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 strain F0386
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