STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGF57696.1Drug resistance MFS transporter, drug:H+ antiporter-2 family; KEGG: tpr:Tpau_0550 2.1e-80 tRNA-guanine transglycosylase, various specificities; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily. (533 aa)    
Predicted Functional Partners:
EGF54286.1
AMP-binding enzyme; KEGG: bur:Bcep18194_B0673 4.4e-238 non-ribosomal peptide synthetase modules K12240; Psort location: Cytoplasmic, score: 9.95.
   
 
 0.697
EGF53505.1
MaoC-like protein; KEGG: bde:BDP_0362 0. fas; fatty acid synthase Fas K11533.
  
 
 0.674
EGF56255.1
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
   
 
  0.669
EGF52726.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
  0.660
EGF57695.1
Transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 7.50.
       0.451
EGF53753.1
Aldehyde dehydrogenase family protein; KEGG: art:Arth_3884 0. L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase K13821; Psort location: Cytoplasmic, score: 9.95.
  
 0.424
EGF55286.1
Hypothetical protein; KEGG: pfr:PFREUD_19900 2.2e-14 pcaC2; 4-carboxymuconolactone decarboxylase.
  
    0.415
EGF56974.1
MATE efflux family protein; KEGG: apb:SAR116_1482 2.5e-15 DNA-damage-inducible protein F K03327; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.414
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.405
EGF57864.1
KEGG: art:Arth_2684 4.2e-107 NAD-dependent epimerase/dehydratase; K01784 UDP-glucose 4-epimerase; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.403
Your Current Organism:
Actinomyces sp. F0386
NCBI taxonomy Id: 762963
Other names: A. sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 strain F0386
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.