STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGF57032.1Hypothetical protein; KEGG: rha:RHA1_ro02466 3.2e-36 spermidine synthase K00797; Psort location: Cytoplasmic, score: 7.50. (258 aa)    
Predicted Functional Partners:
EGF58275.1
Putative S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
  
 
 0.980
EGF55932.1
KEGG: ske:Sked_09810 6.2e-113 diaminopimelate decarboxylase; K01586 diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 7.50.
  
 0.828
speE
Spermine/spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
    
  0.775
argD
Aminotransferase, acetylornithine/succinylornithine family; KEGG: bcv:Bcav_2370 4.8e-122 acetylornithine and succinylornithine aminotransferase K00818; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
     
 0.686
nadE
NAD(+) synthase domain protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.603
EGF58231.1
Aminotransferase; KEGG: pfr:PFREUD_04930 6.0e-131 aspB, (aspC); aspartate/tyrosine/aromatic aminotransferase (transaminase A); Psort location: Cytoplasmic, score: 7.50.
   
  0.601
EGF58057.1
Aspartate transaminase; KEGG: mcu:HMPREF0573_11145 7.3e-165 aspC; aspartate transaminase; Psort location: Cytoplasmic, score: 7.50.
   
  0.601
EGF54286.1
AMP-binding enzyme; KEGG: bur:Bcep18194_B0673 4.4e-238 non-ribosomal peptide synthetase modules K12240; Psort location: Cytoplasmic, score: 9.95.
    
 0.600
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.597
dinB
Putative DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.556
Your Current Organism:
Actinomyces sp. F0386
NCBI taxonomy Id: 762963
Other names: A. sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 strain F0386
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.