STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGF54371.1Peptidase family M13; KEGG: xce:Xcel_1104 1.9e-191 neprilysin K07386; Psort location: Cytoplasmic, score: 9.97. (737 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.647
EGF54372.1
KEGG: ske:Sked_24510 1.1e-56 ribose 5-phosphate isomerase; K01808 ribose 5-phosphate isomerase B; Psort location: Cytoplasmic, score: 7.50.
       0.623
EGF54367.1
Membrane alanyl aminopeptidase; KEGG: cfl:Cfla_1371 8.4e-267 aminopeptidase N; K01256 aminopeptidase N; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.614
EGF55393.1
Aminopeptidase P domain protein; KEGG: mcu:HMPREF0573_10160 3.9e-175 pepPI; Xaa-Pro aminopeptidase K01262; Psort location: Cytoplasmic, score: 9.97; Belongs to the peptidase M24B family.
   
 
 0.607
EGF52556.1
Tat pathway signal sequence domain protein; KEGG: rcu:RCOM_1591990 4.3e-19 Protein Z, putative K13963; Belongs to the serpin family.
    
 0.597
EGF54373.1
Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: ske:Sked_24500 2.4e-79 formamidopyrimidine-DNA glycosylase; K05522 endonuclease VIII; Psort location: Cytoplasmic, score: 7.50; Belongs to the FPG family.
       0.586
truA
Putative tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
      0.574
EGF53558.1
Membrane alanyl aminopeptidase; KEGG: rop:ROP_16210 1.7e-172 pepN; aminopeptidase N K01256; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.509
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.461
EGF54370.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: bfa:Bfae_23940 9.4e-05 subtilisin-like serine protease; K01361 lactocepin.
       0.456
Your Current Organism:
Actinomyces sp. F0386
NCBI taxonomy Id: 762963
Other names: A. sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 strain F0386
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