Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EGF53517.1Conserved domain protein; KEGG: xce:Xcel_0422 0.0019 monosaccharide-transporting ATPase K02057; Psort location: CytoplasmicMembrane, score: 10.00. (560 aa)    
Predicted Functional Partners:
EGF53518.1
Mutacin ABC transporter, ATP-binding protein MutF; KEGG: bao:BAMF_3227 7.1e-48 spaF; SpaF; Psort location: CytoplasmicMembrane, score: 8.78.
       0.823
EGF53519.1
Response regulator receiver domain protein; KEGG: bde:BDP_0818 2.4e-33 two-component response regulator; Psort location: Cytoplasmic, score: 9.97.
       0.529
EGF53520.1
Histidine kinase; KEGG: rer:RER_23020 4.2e-27 two-component histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.529
hisE
KEGG: jde:Jden_1310 6.4e-31 phosphoribosyl-ATP diphosphatase; K01523 phosphoribosyl-ATP pyrophosphohydrolase.
       0.478
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.401
Your Current Organism:
Actinomyces sp. F0386
NCBI taxonomy Id: 762963
Other names: A. sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 strain F0386
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