STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGF53148.1Iron-dependent repressor IdeR; KEGG: apb:SAR116_1403 0.0022 conserved protein, winged helix domain protein K11924; Psort location: Cytoplasmic, score: 9.97. (223 aa)    
Predicted Functional Partners:
EGF53744.1
Transcriptional regulator, Fur family; KEGG: apb:SAR116_1155 2.9e-12 ferric uptake regulation protein, putative K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family.
  
  
 0.682
EGF50243.1
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
    
   0.609
hemA
glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
   
  
 0.539
EGF53149.1
KEGG: gob:Gobs_4597 3.6e-13 major facilitator superfamily MFS_1; K00943 dTMP kinase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.533
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.475
EGF55373.1
KEGG: fal:FRAAL0081 1.7e-55 manganese transport system ATP-binding protein K09820; Psort location: CytoplasmicMembrane, score: 9.99.
  
 
 0.453
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 0.451
EGF52233.1
Type III restriction enzyme, res subunit; KEGG: hvo:HVO_1598 9.2e-07 rad25c; DNA repair helicase RAD25; Psort location: CytoplasmicMembrane, score: 8.16.
 
     0.438
EGF57833.1
UDP-glucose 4-epimerase.
     
 0.436
EGF53150.1
Conserved domain protein; Psort location: Extracellular, score: 8.91.
       0.430
Your Current Organism:
Actinomyces sp. F0386
NCBI taxonomy Id: 762963
Other names: A. sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 str. F0386, Actinomyces sp. oral taxon 170 strain F0386
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.