STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHH01305.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (358 aa)    
Predicted Functional Partners:
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 0.999
EHH00675.1
Riboflavin synthase, alpha subunit.
 
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 0.997
EHH00625.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
   
   0.925
folE
GTP cyclohydrolase I.
    
 0.836
EHH00892.1
Cof-like hydrolase; KEGG: btk:BT9727_5077 1.8e-51 HAD superfamily hydrolase K07024; Psort location: Cytoplasmic, score: 8.96.
    
 0.798
EHG98573.1
Cof-like hydrolase; KEGG: btl:BALH_4896 2.6e-59 HAD superfamily hydrolase K07024; Psort location: Cytoplasmic, score: 8.96.
    
 0.798
hisI
phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family.
    
 0.790
EHH01686.1
HAD hydrolase, family IA, variant 3.
    
 0.787
EHH00654.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
    
 0.787
Your Current Organism:
Paraprevotella clara
NCBI taxonomy Id: 762968
Other names: P. clara YIT 11840, Paraprevotella clara YIT 11840, Paraprevotella clara str. YIT 11840, Paraprevotella clara strain YIT 11840
Server load: low (30%) [HD]