STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHH00936.1Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. (296 aa)    
Predicted Functional Partners:
EHH00935.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
    0.976
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.685
EHG98122.1
Hypothetical protein; KEGG: coc:Coch_1861 4.0e-31 guaA; GMP synthase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.26.
    
  0.685
leuS
leucine--tRNA ligase; KEGG: bvu:BVU_1149 0. leuS; leucyl-tRNA synthetase K01869; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.613
EHH00934.1
Acyltransferase; KEGG: bpu:BPUM_0258 5.9e-21 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.606
EHH00938.1
Hypothetical protein.
       0.545
EHH00933.1
Two component regulator propeller; KEGG: dfe:Dfer_1574 0.0011 histidine kinase; Psort location: Extracellular, score: 9.64.
       0.423
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.401
Your Current Organism:
Paraprevotella clara
NCBI taxonomy Id: 762968
Other names: P. clara YIT 11840, Paraprevotella clara YIT 11840, Paraprevotella clara str. YIT 11840, Paraprevotella clara strain YIT 11840
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.