| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHG98447.1 | EHH01180.1 | HMPREF9441_03554 | HMPREF9441_00843 | Hypothetical protein; KEGG: psl:Psta_4202 1.3e-07 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase; Psort location: Cytoplasmic, score: 8.96. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.938 |
| EHG98447.1 | queC | HMPREF9441_03554 | HMPREF9441_01596 | Hypothetical protein; KEGG: psl:Psta_4202 1.3e-07 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase; Psort location: Cytoplasmic, score: 8.96. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.909 |
| EHG98447.1 | queF | HMPREF9441_03554 | HMPREF9441_01595 | Hypothetical protein; KEGG: psl:Psta_4202 1.3e-07 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase; Psort location: Cytoplasmic, score: 8.96. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.815 |
| EHG99551.1 | queC | HMPREF9441_02574 | HMPREF9441_01596 | KEGG: apb:SAR116_0174 4.0e-06 transcriptional regulator, MerR family; Psort location: Cytoplasmic, score: 8.96. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.513 |
| EHH00362.1 | EHH00363.1 | HMPREF9441_01597 | HMPREF9441_01598 | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | KEGG: pmz:HMPREF0659_A5150 2.0e-20 antioxidant, AhpC/TSA family; Psort location: CytoplasmicMembrane, score: 9.97. | 0.531 |
| EHH00362.1 | EHH00364.1 | HMPREF9441_01597 | HMPREF9441_01599 | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Hypothetical protein. | 0.714 |
| EHH00362.1 | queC | HMPREF9441_01597 | HMPREF9441_01596 | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.819 |
| EHH00362.1 | queF | HMPREF9441_01597 | HMPREF9441_01595 | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.912 |
| EHH00363.1 | EHH00362.1 | HMPREF9441_01598 | HMPREF9441_01597 | KEGG: pmz:HMPREF0659_A5150 2.0e-20 antioxidant, AhpC/TSA family; Psort location: CytoplasmicMembrane, score: 9.97. | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.531 |
| EHH00363.1 | EHH00364.1 | HMPREF9441_01598 | HMPREF9441_01599 | KEGG: pmz:HMPREF0659_A5150 2.0e-20 antioxidant, AhpC/TSA family; Psort location: CytoplasmicMembrane, score: 9.97. | Hypothetical protein. | 0.572 |
| EHH00363.1 | queC | HMPREF9441_01598 | HMPREF9441_01596 | KEGG: pmz:HMPREF0659_A5150 2.0e-20 antioxidant, AhpC/TSA family; Psort location: CytoplasmicMembrane, score: 9.97. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.541 |
| EHH00363.1 | queF | HMPREF9441_01598 | HMPREF9441_01595 | KEGG: pmz:HMPREF0659_A5150 2.0e-20 antioxidant, AhpC/TSA family; Psort location: CytoplasmicMembrane, score: 9.97. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.533 |
| EHH00364.1 | EHH00362.1 | HMPREF9441_01599 | HMPREF9441_01597 | Hypothetical protein. | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.714 |
| EHH00364.1 | EHH00363.1 | HMPREF9441_01599 | HMPREF9441_01598 | Hypothetical protein. | KEGG: pmz:HMPREF0659_A5150 2.0e-20 antioxidant, AhpC/TSA family; Psort location: CytoplasmicMembrane, score: 9.97. | 0.572 |
| EHH00364.1 | queC | HMPREF9441_01599 | HMPREF9441_01596 | Hypothetical protein. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.714 |
| EHH00364.1 | queF | HMPREF9441_01599 | HMPREF9441_01595 | Hypothetical protein. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.714 |
| EHH01180.1 | EHG98447.1 | HMPREF9441_00843 | HMPREF9441_03554 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Hypothetical protein; KEGG: psl:Psta_4202 1.3e-07 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase; Psort location: Cytoplasmic, score: 8.96. | 0.938 |
| EHH01180.1 | queC | HMPREF9441_00843 | HMPREF9441_01596 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.891 |
| EHH01180.1 | queF | HMPREF9441_00843 | HMPREF9441_01595 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.823 |
| murD | queC | HMPREF9441_00252 | HMPREF9441_01596 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.516 |