STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)    
Predicted Functional Partners:
pgi
KEGG: pru:PRU_1785 1.8e-193 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 0.984
EHG99935.1
Fructose-1,6-bisphosphate aldolase, class II; KEGG: bfr:BF3299 3.5e-165 fructose-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.952
fbp
KEGG: bvu:BVU_2901 1.4e-257 fructose-1,6-bisphosphatase; K04041 fructose-1,6-bisphosphatase III; Psort location: Cytoplasmic, score: 8.96.
     
 0.931
EHG98730.1
KEGG: bth:BT_0373 3.3e-91 mannose-6-phosphate isomerase; K01809 mannose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.881
EHG99279.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: pru:PRU_0393 3.6e-291 putative transketolase; K00615 transketolase; Psort location: CytoplasmicMembrane, score: 8.46; Belongs to the transketolase family.
  
 
 0.876
EHH01862.1
KEGG: pru:PRU_2638 4.2e-82 PfkB family kinase; K00847 fructokinase; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.859
EHG98223.1
Kinase, PfkB family; KEGG: bvu:BVU_1665 4.4e-103 fructokinase; K00847 fructokinase; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.859
pfp
Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
 
0.858
EHH01326.1
Pyruvate kinase; KEGG: bvu:BVU_0876 2.7e-213 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 9.97.
 
 0.807
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.791
Your Current Organism:
Paraprevotella clara
NCBI taxonomy Id: 762968
Other names: P. clara YIT 11840, Paraprevotella clara YIT 11840, Paraprevotella clara str. YIT 11840, Paraprevotella clara strain YIT 11840
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.