STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHG99699.1Riboflavin biosynthesis protein RibD protein; KEGG: bpu:BPUM_0485 7.4e-14 dihydrofolate reductase family protein; Psort location: Cytoplasmic, score: 9.97. (172 aa)    
Predicted Functional Partners:
EHH00353.1
Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: pdi:BDI_0415 1.7e-71 putative 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
    
 0.669
EHH00160.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.669
EHG99702.1
Toprim domain protein; KEGG: pmz:HMPREF0659_A6095 0.0021 dnaG_2; DNA primase K02316; Psort location: Cytoplasmic, score: 8.96.
  
    0.627
EHG99638.1
Hypothetical protein; KEGG: lbi:LEPBI_II0025 0.0011 putative ATPase, ParA family K03496; Psort location: Cytoplasmic, score: 8.96.
  
     0.615
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.589
EHG99671.1
KEGG: cai:Caci_5812 1.9e-15 thymidylate synthase K00560; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.589
EHG98494.1
Hypothetical protein; KEGG: mfa:Mfla_0906 2.1e-11 thyA; thymidylate synthase K00560; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.589
EHG98674.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
    0.588
EHG99698.1
Hypothetical protein.
       0.572
EHG98657.1
Relaxase/mobilization nuclease domain protein; KEGG: tin:Tint_2201 2.0e-14 DNA topoisomerase; Psort location: Cytoplasmic, score: 8.96.
  
     0.545
Your Current Organism:
Paraprevotella clara
NCBI taxonomy Id: 762968
Other names: P. clara YIT 11840, Paraprevotella clara YIT 11840, Paraprevotella clara str. YIT 11840, Paraprevotella clara strain YIT 11840
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.