node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHG98833.1 | EHG99389.1 | HMPREF9441_03352 | HMPREF9441_03006 | Hypothetical protein; KEGG: pfa:PFA_0220w 0.00029 ubiquitin carboxyl-terminal hydrolase, putative. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.983 |
EHG98833.1 | EHG99482.1 | HMPREF9441_03352 | HMPREF9441_02611 | Hypothetical protein; KEGG: pfa:PFA_0220w 0.00029 ubiquitin carboxyl-terminal hydrolase, putative. | KEGG: bvu:BVU_1885 0. DNA polymerase III alpha subunit; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97. | 0.490 |
EHG98833.1 | mutS | HMPREF9441_03352 | HMPREF9441_01323 | Hypothetical protein; KEGG: pfa:PFA_0220w 0.00029 ubiquitin carboxyl-terminal hydrolase, putative. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.410 |
EHG98833.1 | polA | HMPREF9441_03352 | HMPREF9441_01343 | Hypothetical protein; KEGG: pfa:PFA_0220w 0.00029 ubiquitin carboxyl-terminal hydrolase, putative. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.755 |
EHG99389.1 | EHG98833.1 | HMPREF9441_03006 | HMPREF9441_03352 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; KEGG: pfa:PFA_0220w 0.00029 ubiquitin carboxyl-terminal hydrolase, putative. | 0.983 |
EHG99389.1 | EHG99390.1 | HMPREF9441_03006 | HMPREF9441_03007 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease; KEGG: bvu:BVU_2893 1.6e-105 DNA Pol III epsilon chain; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96. | 0.992 |
EHG99389.1 | EHG99482.1 | HMPREF9441_03006 | HMPREF9441_02611 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: bvu:BVU_1885 0. DNA polymerase III alpha subunit; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97. | 0.995 |
EHG99389.1 | EHG99523.1 | HMPREF9441_03006 | HMPREF9441_02653 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: bth:BT_3820 2.3e-113 putative DNA polymerase III, delta subunit; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97. | 0.982 |
EHG99389.1 | EHH01661.1 | HMPREF9441_03006 | HMPREF9441_00477 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase V subunit UmuC; KEGG: chu:CHU_1492 1.7e-94 umuC; DNA repair nucleotidyltransferase/DNA polymerase K03502; Psort location: Cytoplasmic, score: 9.97. | 0.983 |
EHG99389.1 | dnaA | HMPREF9441_03006 | HMPREF9441_03401 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.986 |
EHG99389.1 | dnaX | HMPREF9441_03006 | HMPREF9441_01594 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.983 |
EHG99389.1 | mutL | HMPREF9441_03006 | HMPREF9441_03299 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.982 |
EHG99389.1 | mutS | HMPREF9441_03006 | HMPREF9441_01323 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.996 |
EHG99389.1 | polA | HMPREF9441_03006 | HMPREF9441_01343 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
EHG99390.1 | EHG99389.1 | HMPREF9441_03007 | HMPREF9441_03006 | Exonuclease; KEGG: bvu:BVU_2893 1.6e-105 DNA Pol III epsilon chain; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.992 |
EHG99390.1 | EHG99482.1 | HMPREF9441_03007 | HMPREF9441_02611 | Exonuclease; KEGG: bvu:BVU_2893 1.6e-105 DNA Pol III epsilon chain; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96. | KEGG: bvu:BVU_1885 0. DNA polymerase III alpha subunit; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97. | 0.964 |
EHG99390.1 | EHG99523.1 | HMPREF9441_03007 | HMPREF9441_02653 | Exonuclease; KEGG: bvu:BVU_2893 1.6e-105 DNA Pol III epsilon chain; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT_3820 2.3e-113 putative DNA polymerase III, delta subunit; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97. | 0.951 |
EHG99390.1 | dnaX | HMPREF9441_03007 | HMPREF9441_01594 | Exonuclease; KEGG: bvu:BVU_2893 1.6e-105 DNA Pol III epsilon chain; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.951 |
EHG99390.1 | polA | HMPREF9441_03007 | HMPREF9441_01343 | Exonuclease; KEGG: bvu:BVU_2893 1.6e-105 DNA Pol III epsilon chain; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.661 |
EHG99482.1 | EHG98833.1 | HMPREF9441_02611 | HMPREF9441_03352 | KEGG: bvu:BVU_1885 0. DNA polymerase III alpha subunit; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: pfa:PFA_0220w 0.00029 ubiquitin carboxyl-terminal hydrolase, putative. | 0.490 |