STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHG99424.1Arabinose 5-phosphate isomerase; KEGG: pru:PRU_1627 6.3e-120 sugar isomerase, KpsF/GutQ family; K06041 arabinose-5-phosphate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SIS family. GutQ/KpsF subfamily. (316 aa)    
Predicted Functional Partners:
EHG99425.1
KEGG: pru:PRU_0445 4.3e-105 kdsA_1; 3-deoxy-8-phosphooctulonate synthase K01627; Psort location: Cytoplasmic, score: 9.97; Belongs to the KdsA family.
 
 
 0.996
EHH00308.1
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: bvu:BVU_2497 1.0e-71 putative hydrolase; K03270 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase); Psort location: Cytoplasmic, score: 9.97.
 
 0.946
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 0.916
EHG98122.1
Hypothetical protein; KEGG: coc:Coch_1861 4.0e-31 guaA; GMP synthase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 9.26.
  
 0.916
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.883
EHG99598.1
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 
 0.838
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.831
EHG98365.1
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.830
EHH00734.1
K+-dependent Na+/Ca+ exchanger family protein; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.823
EHH00555.1
KEGG: bvu:BVU_4007 0. glutamate synthase, large subunit; K00265 glutamate synthase (NADPH/NADH) large chain.
    
 0.822
Your Current Organism:
Paraprevotella clara
NCBI taxonomy Id: 762968
Other names: P. clara YIT 11840, Paraprevotella clara YIT 11840, Paraprevotella clara str. YIT 11840, Paraprevotella clara strain YIT 11840
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.