| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHG99075.1 | EHG99076.1 | HMPREF9441_03223 | HMPREF9441_03224 | Amino acid kinase family protein; Belongs to the aspartokinase family. | Putative cell division ATP-binding protein FtsE. | 0.773 |
| EHG99075.1 | EHG99082.1 | HMPREF9441_03223 | HMPREF9441_03230 | Amino acid kinase family protein; Belongs to the aspartokinase family. | ABC transporter, ATP-binding protein. | 0.484 |
| EHG99075.1 | EHG99084.1 | HMPREF9441_03223 | HMPREF9441_03232 | Amino acid kinase family protein; Belongs to the aspartokinase family. | Hypothetical protein. | 0.403 |
| EHG99075.1 | hisA | HMPREF9441_03223 | HMPREF9441_03227 | Amino acid kinase family protein; Belongs to the aspartokinase family. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | 0.688 |
| EHG99075.1 | hisF | HMPREF9441_03223 | HMPREF9441_03226 | Amino acid kinase family protein; Belongs to the aspartokinase family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.747 |
| EHG99075.1 | hisH | HMPREF9441_03223 | HMPREF9441_03228 | Amino acid kinase family protein; Belongs to the aspartokinase family. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.633 |
| EHG99075.1 | hisI | HMPREF9441_03223 | HMPREF9441_03225 | Amino acid kinase family protein; Belongs to the aspartokinase family. | phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.801 |
| EHG99075.1 | ruvC | HMPREF9441_03223 | HMPREF9441_03231 | Amino acid kinase family protein; Belongs to the aspartokinase family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.403 |
| EHG99076.1 | EHG99075.1 | HMPREF9441_03224 | HMPREF9441_03223 | Putative cell division ATP-binding protein FtsE. | Amino acid kinase family protein; Belongs to the aspartokinase family. | 0.773 |
| EHG99076.1 | EHG99082.1 | HMPREF9441_03224 | HMPREF9441_03230 | Putative cell division ATP-binding protein FtsE. | ABC transporter, ATP-binding protein. | 0.420 |
| EHG99076.1 | EHG99084.1 | HMPREF9441_03224 | HMPREF9441_03232 | Putative cell division ATP-binding protein FtsE. | Hypothetical protein. | 0.417 |
| EHG99076.1 | hisA | HMPREF9441_03224 | HMPREF9441_03227 | Putative cell division ATP-binding protein FtsE. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | 0.717 |
| EHG99076.1 | hisF | HMPREF9441_03224 | HMPREF9441_03226 | Putative cell division ATP-binding protein FtsE. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.717 |
| EHG99076.1 | hisH | HMPREF9441_03224 | HMPREF9441_03228 | Putative cell division ATP-binding protein FtsE. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.717 |
| EHG99076.1 | hisI | HMPREF9441_03224 | HMPREF9441_03225 | Putative cell division ATP-binding protein FtsE. | phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.788 |
| EHG99076.1 | ruvC | HMPREF9441_03224 | HMPREF9441_03231 | Putative cell division ATP-binding protein FtsE. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.417 |
| EHG99082.1 | EHG99075.1 | HMPREF9441_03230 | HMPREF9441_03223 | ABC transporter, ATP-binding protein. | Amino acid kinase family protein; Belongs to the aspartokinase family. | 0.484 |
| EHG99082.1 | EHG99076.1 | HMPREF9441_03230 | HMPREF9441_03224 | ABC transporter, ATP-binding protein. | Putative cell division ATP-binding protein FtsE. | 0.420 |
| EHG99082.1 | EHG99084.1 | HMPREF9441_03230 | HMPREF9441_03232 | ABC transporter, ATP-binding protein. | Hypothetical protein. | 0.774 |
| EHG99082.1 | EHG99085.1 | HMPREF9441_03230 | HMPREF9441_03233 | ABC transporter, ATP-binding protein. | Fibronectin type III domain protein. | 0.465 |