STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHG98840.1UvrD/REP helicase; KEGG: eat:EAT1b_1102 2.4e-127 UvrD/REP helicase; K03658 DNA helicase IV; Psort location: Cytoplasmic, score: 9.97. (939 aa)    
Predicted Functional Partners:
EHH00630.1
KEGG: bvu:BVU_3787 0. pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
  
   0.934
EHH00642.1
KEGG: bvu:BVU_2070 3.1e-212 ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97.
  
 0.886
EHG98773.1
ATP-dependent DNA helicase RecQ.
  
 0.886
EHG98270.1
KEGG: bfs:BF3249 2.2e-218 recQ2; putative ATP-dependent DNA helicase K03654; Psort location: Cytoplasmic, score: 9.97.
  
 0.886
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.857
EHG99389.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.843
EHG99220.1
KEGG: shn:Shewana3_3590 1.2e-24 single-strand binding protein K03111; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.834
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.822
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.800
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.790
Your Current Organism:
Paraprevotella clara
NCBI taxonomy Id: 762968
Other names: P. clara YIT 11840, Paraprevotella clara YIT 11840, Paraprevotella clara str. YIT 11840, Paraprevotella clara strain YIT 11840
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