STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaAReplication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (468 aa)    
Predicted Functional Partners:
EHG99389.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.986
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
 0.866
EHH01977.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 
 0.829
EHH00079.1
DnaB-like helicase protein; KEGG: bvu:BVU_3467 7.2e-71 DNA helicase; K02314 replicative DNA helicase; Psort location: Cytoplasmic, score: 9.97.
  
 
 
 0.810
EHH00015.1
KEGG: sub:SUB0808 1.8e-186 pyridine nucleotide-disulphide oxidoreductase family protein; Psort location: Cytoplasmic, score: 9.97; Belongs to the sulfur carrier protein TusA family.
  
    0.758
EHG98654.1
Hypothetical protein.
    
 
 0.690
EHG99892.1
Tetrapyrrole methylase; KEGG: gfo:GFO_0628 7.3e-55 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase K07056; Psort location: Cytoplasmic, score: 8.96.
 
    0.688
EHG98883.1
Hypothetical protein.
       0.686
EHG99546.1
Putative stage 0 sporulation protein J; KEGG: cti:RALTA_A3100 9.8e-51 parB1; exonuclease involved in chromosome partitioning, ParB protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family.
 
  
 0.625
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
  
 0.610
Your Current Organism:
Paraprevotella clara
NCBI taxonomy Id: 762968
Other names: P. clara YIT 11840, Paraprevotella clara YIT 11840, Paraprevotella clara str. YIT 11840, Paraprevotella clara strain YIT 11840
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.