Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EGF51716.1Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (303 aa)    
Predicted Functional Partners:
EGF51717.1
23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: bfs:BF2568 2.6e-233 putative RNA methyltransferase; K00599; Psort location: Cytoplasmic, score: 9.97; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
  
 0.788
EGF51718.1
KEGG: bfs:BF2567 0. ppdK; pyruvate phosphate dikinase K01006; Psort location: Cytoplasmic, score: 9.97; Belongs to the PEP-utilizing enzyme family.
       0.642
EGF58937.1
KEGG: bfr:BF1660 2.6e-194 ATP-dependent RNA helicase DeaD; K11927 ATP-dependent RNA helicase RhlE; Psort location: Cytoplasmic, score: 9.97; Belongs to the DEAD box helicase family.
 
 
 
 0.603
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
 
 0.594
EGF57469.1
RNA methyltransferase, TrmH family; KEGG: bth:BT_4513 2.0e-116 putative rRNA methylase; K00599; Psort location: Cytoplasmic, score: 9.26.
 
 
 0.594
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.592
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.584
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.581
rplQ
Ribosomal protein L17; KEGG: apb:SAR116_2416 8.6e-20 ribosomal protein L17 K02879; Psort location: Cytoplasmic, score: 9.26.
  
   0.581
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.581
Your Current Organism:
Bacteroides fluxus
NCBI taxonomy Id: 763034
Other names: B. fluxus YIT 12057, Bacteroides fluxus DSM 22534, Bacteroides fluxus JCM 16101, Bacteroides fluxus YIT 12057, Bacteroides fluxus str. YIT 12057, Bacteroides fluxus strain YIT 12057, Bacteroides sp. YIT 12057
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