A0A162NDE2 protein (Phycomyces blakesleeanus)

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A0A162NDE2

Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (480 aa)

Predicted Functional Partners:

A0A167KIK1

0.839

A0A163ASE1

0.754

A0A162Q5D3

0.698

A0A163BAF6

0.689

A0A167KJ72

0.677

A0A162PWG2

0.674

A0A162XA42

0.674

A0A167R8V7

0.668

A0A167N067

0.667

A0A162UFN6

0.665

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A162NDE2	A0A162PWG2	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.674
A0A162NDE2	A0A162Q5D3	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Uncharacterized protein.	0.698
A0A162NDE2	A0A162UFN6	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Pribosyltran domain-containing protein.	0.665
A0A162NDE2	A0A162XA42	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Guanylate kinase-like domain-containing protein.	0.674
A0A162NDE2	A0A163ASE1	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Uncharacterized protein.	0.754
A0A162NDE2	A0A163BAF6	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.689
A0A162NDE2	A0A167KIK1	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	0.839
A0A162NDE2	A0A167KJ72	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.677
A0A162NDE2	A0A167N067	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.667
A0A162NDE2	A0A167R8V7	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	NDK domain-containing protein; Belongs to the NDK family.	0.668
A0A162PWG2	A0A162NDE2	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	0.674
A0A162PWG2	A0A162Q5D3	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Uncharacterized protein.	0.897
A0A162PWG2	A0A162UFN6	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Pribosyltran domain-containing protein.	0.862
A0A162PWG2	A0A162XA42	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Guanylate kinase-like domain-containing protein.	0.892
A0A162PWG2	A0A163ASE1	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Uncharacterized protein.	0.747
A0A162PWG2	A0A163BAF6	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.921
A0A162PWG2	A0A167KIK1	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	0.814
A0A162PWG2	A0A167KJ72	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.906
A0A162PWG2	A0A167N067	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.522
A0A162PWG2	A0A167R8V7	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	NDK domain-containing protein; Belongs to the NDK family.	0.854