STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mo00538Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (565 aa)    
Predicted Functional Partners:
Mo02837
Pterin-binding domain-containing protein.
 
 
 0.967
Mo04094
Thymidylat_synt domain-containing protein.
     
 0.852
Mo00755
FSH1 domain-containing protein.
     
 0.830
Mo04186
Mur_ligase_M domain-containing protein.
  
  
0.821
Mo05127
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.813
Mo06634
Uncharacterized protein.
  
 
 0.795
Mo02920
SHMT domain-containing protein.
  
 0.792
Mo04082
Uncharacterized protein.
    
 0.756
Mo05853
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.727
Mo03642
Glutamine amidotransferase type-1 domain-containing protein.
     
 0.706
Your Current Organism:
Mixia osmundae
NCBI taxonomy Id: 764103
Other names: M. osmundae IAM 14324, Mixia osmundae IAM 14324
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