node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mo00538 | Mo00755 | G7DTP5 | G7DU48 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | FSH1 domain-containing protein. | 0.830 |
Mo00538 | Mo02837 | G7DTP5 | G7E013 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Pterin-binding domain-containing protein. | 0.967 |
Mo00538 | Mo02920 | G7DTP5 | G7E096 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | SHMT domain-containing protein. | 0.792 |
Mo00538 | Mo03642 | G7DTP5 | G7E2A8 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Glutamine amidotransferase type-1 domain-containing protein. | 0.706 |
Mo00538 | Mo04082 | G7DTP5 | G7E3J4 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Uncharacterized protein. | 0.756 |
Mo00538 | Mo04094 | G7DTP5 | G7E3K6 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylat_synt domain-containing protein. | 0.852 |
Mo00538 | Mo04186 | G7DTP5 | G7E3U8 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Mur_ligase_M domain-containing protein. | 0.821 |
Mo00538 | Mo05127 | G7DTP5 | G7E6I1 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.813 |
Mo00538 | Mo05853 | G7DTP5 | G7E8K1 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.727 |
Mo00538 | Mo06634 | G7DTP5 | G7EAS1 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Uncharacterized protein. | 0.795 |
Mo00755 | Mo00538 | G7DU48 | G7DTP5 | FSH1 domain-containing protein. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.830 |
Mo00755 | Mo02837 | G7DU48 | G7E013 | FSH1 domain-containing protein. | Pterin-binding domain-containing protein. | 0.817 |
Mo00755 | Mo02920 | G7DU48 | G7E096 | FSH1 domain-containing protein. | SHMT domain-containing protein. | 0.961 |
Mo00755 | Mo03642 | G7DU48 | G7E2A8 | FSH1 domain-containing protein. | Glutamine amidotransferase type-1 domain-containing protein. | 0.658 |
Mo00755 | Mo04082 | G7DU48 | G7E3J4 | FSH1 domain-containing protein. | Uncharacterized protein. | 0.817 |
Mo00755 | Mo04094 | G7DU48 | G7E3K6 | FSH1 domain-containing protein. | Thymidylat_synt domain-containing protein. | 0.990 |
Mo00755 | Mo04186 | G7DU48 | G7E3U8 | FSH1 domain-containing protein. | Mur_ligase_M domain-containing protein. | 0.830 |
Mo00755 | Mo05127 | G7DU48 | G7E6I1 | FSH1 domain-containing protein. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.551 |
Mo00755 | Mo05853 | G7DU48 | G7E8K1 | FSH1 domain-containing protein. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.676 |
Mo00755 | Mo06634 | G7DU48 | G7EAS1 | FSH1 domain-containing protein. | Uncharacterized protein. | 0.957 |