node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mo00348 | Mo00816 | G7DSZ3 | G7DUA8 | Guanylate kinase-like domain-containing protein. | Uncharacterized protein; Belongs to the NDK family. | 0.934 |
Mo00348 | Mo01240 | G7DSZ3 | G7DVH8 | Guanylate kinase-like domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.869 |
Mo00348 | Mo01919 | G7DSZ3 | G7DXF3 | Guanylate kinase-like domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.445 |
Mo00348 | Mo02769 | G7DSZ3 | G7DZU8 | Guanylate kinase-like domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.946 |
Mo00348 | Mo03352 | G7DSZ3 | G7E1H1 | Guanylate kinase-like domain-containing protein. | Pribosyltran domain-containing protein. | 0.958 |
Mo00348 | Mo04973 | G7DSZ3 | G7E629 | Guanylate kinase-like domain-containing protein. | dUTPase domain-containing protein. | 0.497 |
Mo00348 | Mo05862 | G7DSZ3 | G7E951 | Guanylate kinase-like domain-containing protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.920 |
Mo00348 | Mo06506 | G7DSZ3 | G7EAE3 | Guanylate kinase-like domain-containing protein. | Uncharacterized protein. | 0.949 |
Mo00816 | Mo00348 | G7DUA8 | G7DSZ3 | Uncharacterized protein; Belongs to the NDK family. | Guanylate kinase-like domain-containing protein. | 0.934 |
Mo00816 | Mo01240 | G7DUA8 | G7DVH8 | Uncharacterized protein; Belongs to the NDK family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.437 |
Mo00816 | Mo01919 | G7DUA8 | G7DXF3 | Uncharacterized protein; Belongs to the NDK family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.440 |
Mo00816 | Mo02311 | G7DUA8 | G7DYJ5 | Uncharacterized protein; Belongs to the NDK family. | GTP_cyclohydroI domain-containing protein. | 0.854 |
Mo00816 | Mo02769 | G7DUA8 | G7DZU8 | Uncharacterized protein; Belongs to the NDK family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.940 |
Mo00816 | Mo03352 | G7DUA8 | G7E1H1 | Uncharacterized protein; Belongs to the NDK family. | Pribosyltran domain-containing protein. | 0.431 |
Mo00816 | Mo04973 | G7DUA8 | G7E629 | Uncharacterized protein; Belongs to the NDK family. | dUTPase domain-containing protein. | 0.926 |
Mo00816 | Mo05862 | G7DUA8 | G7E951 | Uncharacterized protein; Belongs to the NDK family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.909 |
Mo01240 | Mo00348 | G7DVH8 | G7DSZ3 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Guanylate kinase-like domain-containing protein. | 0.869 |
Mo01240 | Mo00816 | G7DVH8 | G7DUA8 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein; Belongs to the NDK family. | 0.437 |
Mo01240 | Mo01919 | G7DVH8 | G7DXF3 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.993 |
Mo01240 | Mo02311 | G7DVH8 | G7DYJ5 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | GTP_cyclohydroI domain-containing protein. | 0.465 |