STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (333 aa)    
Predicted Functional Partners:
mvaD
Diphosphomevalonate decarboxylase.
 
  
 0.986
EHJ56365.1
Phosphomevalonate kinase.
 
 0.982
mvk
Mevalonate kinase.
 
 
 0.975
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.908
EHJ56540.1
hydroxymethylglutaryl-CoA synthase.
 
 
 0.901
EHJ56319.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.883
EHJ56003.1
hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
   
 0.869
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.848
lpdA_1
Dihydrolipoyl dehydrogenase.
     
 0.794
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.618
Your Current Organism:
Streptococcus urinalis
NCBI taxonomy Id: 764291
Other names: S. urinalis 2285-97, Streptococcus urinalis 2285-97, Streptococcus urinalis CCUG 41590, Streptococcus urinalis CDC 2285-97, Streptococcus urinalis CIP 106463, Streptococcus urinalis DSM 16830, Streptococcus urinalis LMG 19649, Streptococcus urinalis str. 2285-97, Streptococcus urinalis strain 2285-97
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