Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
radCDNA repair protein RadC; Belongs to the UPF0758 family. (226 aa)    
Predicted Functional Partners:
EHJ57700.1
Putative membrane protein.
  
    0.782
EHJ55850.1
DEAD/DEAH box helicase.
      
 0.695
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 
   
 0.681
cinA
Competence/damage-inducible protein CinA; Belongs to the CinA family.
     
 0.638
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
 0.634
EHJ56429.1
DNA/RNA non-specific endonuclease-like protein.
  
   
 0.613
dprA
DNA protecting protein DprA.
   
  
 0.583
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
   
 0.566
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.550
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.530
Your Current Organism:
Streptococcus urinalis
NCBI taxonomy Id: 764291
Other names: S. urinalis 2285-97, Streptococcus urinalis 2285-97, Streptococcus urinalis CCUG 41590, Streptococcus urinalis CDC 2285-97, Streptococcus urinalis CIP 106463, Streptococcus urinalis DSM 16830, Streptococcus urinalis LMG 19649, Streptococcus urinalis str. 2285-97, Streptococcus urinalis strain 2285-97
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