Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHJ52855.1Phosphomevalonate kinase. (332 aa)    
Predicted Functional Partners:
mvaD
Diphosphomevalonate decarboxylase.
 
 
 0.999
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 0.993
mvk
Mevalonate kinase.
 
  
 0.978
EHJ52868.1
hydroxymethylglutaryl-CoA synthase.
 
 
 0.952
EHJ51880.1
hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
 
 0.917
EHJ52589.1
3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal domain protein.
  
 
 0.705
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
      
 0.560
EHJ52259.1
Hypothetical protein.
 
     0.488
pheT
phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.459
EHJ51803.1
Beta-ketoacyl synthase, N-terminal domain protein.
   
 
 0.446
Your Current Organism:
Streptococcus macacae
NCBI taxonomy Id: 764298
Other names: S. macacae NCTC 11558, Streptococcus macacae ATCC 35911, Streptococcus macacae CCUG 27653, Streptococcus macacae CIP 102912, Streptococcus macacae LMG 15097, Streptococcus macacae NCTC 11558, Streptococcus macacae str. NCTC 11558, Streptococcus macacae strain NCTC 11558
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