Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHJ52254.1Carboxymuconolactone decarboxylase family protein. (106 aa)    
Predicted Functional Partners:
EHJ52458.1
Cupin domain protein.
  
 0.994
EHJ52589.1
3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal domain protein.
  
 
  0.665
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.621
EHJ51675.1
Putative HTH-type transcriptional regulator AdhR.
       0.568
adh
Aldehyde-alcohol dehydrogenase 2; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
  0.469
EHJ53191.1
3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein.
  
 
 0.467
cdsA
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
     
  0.438
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.436
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.434
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.426
Your Current Organism:
Streptococcus macacae
NCBI taxonomy Id: 764298
Other names: S. macacae NCTC 11558, Streptococcus macacae ATCC 35911, Streptococcus macacae CCUG 27653, Streptococcus macacae CIP 102912, Streptococcus macacae LMG 15097, Streptococcus macacae NCTC 11558, Streptococcus macacae str. NCTC 11558, Streptococcus macacae strain NCTC 11558
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