Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EHJ53075.1Hypothetical protein. (236 aa)    
Predicted Functional Partners:
EHJ52418.1
Dinuclear metal center protein, YbgI family.
  
 0.977
EHJ51795.1
Replication initiation and membrane attachment protein, DnaB/DnaD family.
 
     0.887
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
       0.860
EHJ51864.1
Helix-turn-helix protein, YlxM/p13 family; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.751
EHJ53304.1
FAD dependent oxidoreductase.
       0.731
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.718
EHJ52655.1
Hypothetical protein; Belongs to the UPF0297 family.
  
     0.713
EHJ51645.1
Putative dTDP-4-dehydrorhamnose 3,5-epimerase.
       0.662
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
       0.662
addA
Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.
 
     0.632
Your Current Organism:
Streptococcus macacae
NCBI taxonomy Id: 764298
Other names: S. macacae NCTC 11558, Streptococcus macacae ATCC 35911, Streptococcus macacae CCUG 27653, Streptococcus macacae CIP 102912, Streptococcus macacae LMG 15097, Streptococcus macacae NCTC 11558, Streptococcus macacae str. NCTC 11558, Streptococcus macacae strain NCTC 11558
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