Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHJ52567.1KR domain protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)    
Predicted Functional Partners:
EHJ52619.1
AMP-binding enzyme.
 
 0.976
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
 
 
  0.914
EHJ52313.1
AMP-binding enzyme; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.
  
 
 0.855
EHJ51803.1
Beta-ketoacyl synthase, N-terminal domain protein.
  
 
 0.840
EHJ52978.1
HTH-type transcriptional regulator CueR family protein.
       0.773
EHJ52705.1
Beta-ketoacyl synthase, N-terminal domain protein.
  
 
 0.741
EHJ52051.1
Putative linear gramicidin synthetase LgrD; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.
  
 0.686
EHJ53240.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
  0.675
EHJ52015.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein.
      
 0.613
EHJ51710.1
Transcriptional regulatory protein, C-terminal domain protein.
      
 0.595
Your Current Organism:
Streptococcus macacae
NCBI taxonomy Id: 764298
Other names: S. macacae NCTC 11558, Streptococcus macacae ATCC 35911, Streptococcus macacae CCUG 27653, Streptococcus macacae CIP 102912, Streptococcus macacae LMG 15097, Streptococcus macacae NCTC 11558, Streptococcus macacae str. NCTC 11558, Streptococcus macacae strain NCTC 11558
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