Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHJ53335.1O-methyltransferase. (223 aa)    
Predicted Functional Partners:
EHJ52619.1
AMP-binding enzyme.
  
 0.905
prsA
PPIC-type PPIASE domain protein; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
       0.756
EHJ51637.1
Peptidase, U32 family.
 
  
 0.728
EHJ52660.1
HAD hydrolase, family IA, variant 1.
       0.722
EHJ52313.1
AMP-binding enzyme; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.
     
 0.712
pepF
Oligoendopeptidase F.
       0.703
EHJ51898.1
CoiA-like protein.
       0.702
EHJ53318.1
Peptidase, U32 family.
 
  
 0.698
EHJ51786.1
Hypothetical protein.
 
     0.665
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.587
Your Current Organism:
Streptococcus macacae
NCBI taxonomy Id: 764298
Other names: S. macacae NCTC 11558, Streptococcus macacae ATCC 35911, Streptococcus macacae CCUG 27653, Streptococcus macacae CIP 102912, Streptococcus macacae LMG 15097, Streptococcus macacae NCTC 11558, Streptococcus macacae str. NCTC 11558, Streptococcus macacae strain NCTC 11558
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