Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHJ52128.1Bacterial regulatory protein, GntR family. (457 aa)    
Predicted Functional Partners:
lpdA
Dihydrolipoyl dehydrogenase.
     
  0.650
EHJ52313.1
AMP-binding enzyme; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.
  
 
 0.641
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.626
glnA
Glutamine synthetase, type I.
    
  0.620
pdxB
4-phosphoerythronate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.597
EHJ52619.1
AMP-binding enzyme.
  
 
 0.581
EHJ52736.1
Oxidoreductase, zinc-binding dehydrogenase family protein.
  
    0.538
EHJ52418.1
Dinuclear metal center protein, YbgI family.
   
    0.446
gor
Glutathione-disulfide reductase.
     
  0.443
EHJ52353.1
Pyridine nucleotide-disulfide oxidoreductase.
     
  0.443
Your Current Organism:
Streptococcus macacae
NCBI taxonomy Id: 764298
Other names: S. macacae NCTC 11558, Streptococcus macacae ATCC 35911, Streptococcus macacae CCUG 27653, Streptococcus macacae CIP 102912, Streptococcus macacae LMG 15097, Streptococcus macacae NCTC 11558, Streptococcus macacae str. NCTC 11558, Streptococcus macacae strain NCTC 11558
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