Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EHJ52764.1Transcriptional regulator, AraC family. (325 aa)    
Predicted Functional Partners:
EHJ52619.1
AMP-binding enzyme.
     
 0.690
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.658
EHJ53364.1
Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.612
EHJ52689.1
Histidine kinase.
    
 0.538
EHJ53191.1
3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein.
  
  
 0.534
EHJ53290.1
Nitroreductase family protein.
  
     0.498
EHJ53092.1
Response regulator receiver domain protein.
     
  0.485
EHJ51997.1
Transcriptional regulator, TetR family.
  
     0.446
EHJ52520.1
Aldehyde dehydrogenase (NAD) domain protein.
 
   
 0.439
EHJ52313.1
AMP-binding enzyme; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.
 
  
 0.437
Your Current Organism:
Streptococcus macacae
NCBI taxonomy Id: 764298
Other names: S. macacae NCTC 11558, Streptococcus macacae ATCC 35911, Streptococcus macacae CCUG 27653, Streptococcus macacae CIP 102912, Streptococcus macacae LMG 15097, Streptococcus macacae NCTC 11558, Streptococcus macacae str. NCTC 11558, Streptococcus macacae strain NCTC 11558
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