Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHI70790.1Bacterial ABC transporter protein EcsB domain protein. (344 aa)    
Predicted Functional Partners:
EHI70808.1
ABC transporter, ATP-binding protein.
 
  
 0.925
prsA
Putative foldase protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
 
   
 0.810
EHI70983.1
Choline/ethanolamine kinase.
 
     0.783
divIB
POTRA domain protein, FtsQ-type; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
     0.763
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
   
 0.739
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.736
mecA
Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
     0.734
hit
Protein hit.
     
 0.733
EHI68685.1
Tetratricopeptide repeat protein.
  
     0.732
rpoE
DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.720
Your Current Organism:
Streptococcus ictaluri
NCBI taxonomy Id: 764299
Other names: S. ictaluri 707-05, Streptococcus ictaluri 707-05, Streptococcus ictaluri str. 707-05, Streptococcus ictaluri strain 707-05
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