Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHI69787.1Hypothetical protein. (329 aa)    
Predicted Functional Partners:
EHI69408.1
Glyoxalase family protein.
       0.618
EHI69760.1
Sortase family protein.
       0.581
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.581
EHI69730.1
Hypothetical protein.
      
 0.557
cvpA
Colicin V production protein.
  
     0.545
EHI69334.1
Periplasmic solute-binding family protein; Belongs to the bacterial solute-binding protein 9 family.
       0.515
EHI69554.1
Histidine triad domain protein.
       0.509
EHI69748.1
FemAB domain protein.
       0.466
EHI69879.1
ABC transporter, ATP-binding protein.
   
    0.422
EHI68601.1
Penicillin-binding protein dimerization domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
 
     0.417
Your Current Organism:
Streptococcus ictaluri
NCBI taxonomy Id: 764299
Other names: S. ictaluri 707-05, Streptococcus ictaluri 707-05, Streptococcus ictaluri str. 707-05, Streptococcus ictaluri strain 707-05
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