Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mvaDDiphosphomevalonate decarboxylase. (287 aa)    
Predicted Functional Partners:
EHI69848.1
Phosphomevalonate kinase.
 
 
 0.999
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.998
mvk
Mevalonate kinase.
 
 
 0.993
EHI69506.1
hydroxymethylglutaryl-CoA synthase.
 
 
 0.955
EHI69713.1
hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
 
 
 0.950
EHI68619.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.945
EHI69253.1
Hydrolase, NUDIX family.
  
 
 0.791
EHI69384.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.666
EHI69015.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.666
lysS
lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
    0.591
Your Current Organism:
Streptococcus ictaluri
NCBI taxonomy Id: 764299
Other names: S. ictaluri 707-05, Streptococcus ictaluri 707-05, Streptococcus ictaluri str. 707-05, Streptococcus ictaluri strain 707-05
Server load: low (28%) [HD]