Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHI69676.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (307 aa)    
Predicted Functional Partners:
EHI69357.1
PTS system, IIC component family protein.
 
   
 0.948
EHI69763.1
Transcriptional regulator, DeoR family.
  
    0.651
EHI69432.1
Pyridine nucleotide-disulfide oxidoreductase.
     
 0.602
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.599
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase.
    
 0.578
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.577
EHI69528.1
Pyrimidine-nucleoside phosphorylase.
      
 0.528
EHI69833.1
Putative membrane protein.
 
   
 0.520
EHI69557.1
1-phosphofructokinase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.
       0.515
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
       0.513
Your Current Organism:
Streptococcus ictaluri
NCBI taxonomy Id: 764299
Other names: S. ictaluri 707-05, Streptococcus ictaluri 707-05, Streptococcus ictaluri str. 707-05, Streptococcus ictaluri strain 707-05
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