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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64320.1Hypothetical protein; KEGG: cma:Cmaq_1061 IS605 family transposase OrfB; SPTR: Transposase, IS605 OrfB family. (60 aa)    
Predicted Functional Partners:
ADV65305.1
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; InterPro IPR006137: IPR001268; KEGG: dka:DKAM_0955 NADH-quinone oxidoreductase, B subunit; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH-quinone oxidoreductase, B subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; NADH ubiquinone oxidoreductase, 20 Kd subunit.
   
  
 0.804
ADV64321.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
     
 0.666
ADV64322.1
Protein of unknown function DUF99; COGs: COG1628 conserved hypothetical protein; InterPro IPR002802; KEGG: dka:DKAM_1378 protein of unknown function DUF99; PFAM: protein of unknown function DUF99; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF99; Belongs to the UPF0215 family.
       0.607
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  
 0.486
ADV64373.1
COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017900: IPR017896; KEGG: dka:DKAM_1022 hydrogenase 4 Fe-S subunit; SPTR: Hydrogenase 4 Fe-S subunit; PFAM: 4Fe-4S binding domain.
  
  
 0.485
ADV65119.1
COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017900: IPR017896; KEGG: dka:DKAM_0416 NADH-ubiquinone oxidoreductase, subunit I; SPTR: NADH-ubiquinone oxidoreductase, subunit I; PFAM: 4Fe-4S binding domain.
  
  
 0.485
ADV65307.1
COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017900: IPR017896; KEGG: dka:DKAM_0953 NuoI NADH dehydrogenase I, subunit I; SPTR: NuoI NADH dehydrogenase I, subunit I; PFAM: 4Fe-4S binding domain.
  
  
 0.485
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
       0.420
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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