Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADV64329.1Ras superfamily GTP-binding protein YlqF; COGs: COG1161 GTPase; InterPro IPR016478: IPR002917; KEGG: dka:DKAM_1385 GTP-binding protein, HSR1-related; PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein, HSR1-related; PFAM: GTPase of unknown function; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (286 aa)    
Predicted Functional Partners:
ADV65566.1
Small GTP-binding protein; COGs: COG1084 GTPase; InterPro IPR002917: IPR006073: IPR005225; KEGG: dka:DKAM_1284 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
  
 
 0.975
flpA
rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.945
rps8e
COGs: COG2007 Ribosomal protein S8E; InterPro IPR018283: IPR020919: IPR001047; KEGG: dka:DKAM_0926 30S ribosomal protein S8e; SPTR: 30S ribosomal protein S8e; TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8e; TIGRFAM: ribosomal protein S8.e.
   
 
 0.937
rpl30
LSU ribosomal protein L30P; InterPro IPR005997: IPR000517; KEGG: dka:DKAM_1154 50S ribosomal protein L30P; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30P; TIGRFAM: ribosomal protein L30P; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: 50S ribosomal protein L30P, archaeal.
   
 
 0.937
rpl10
LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.921
ADV64644.1
KEGG: dka:DKAM_0585 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0113).
   
 
 0.914
ADV65170.1
COGs: COG1498 Protein implicated in ribosomal biogenesis Nop56p homolog; InterPro IPR012976: IPR002687; KEGG: dka:DKAM_0815 C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; SPTR: Pre-mRNA processing ribonucleoprotein, binding region; PFAM: Putative snoRNA binding domain; NOSIC (NUC001) domain.
  
 
 0.905
ADV65606.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
   
 
 0.905
ADV64328.1
Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
  
    0.891
rpl18
LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 
 0.885
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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