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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64368.1COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029: IPR011488; KEGG: dka:DKAM_1424 translation initiation factor IF-2 subunit alpha; PFAM: translation initiation factor 2, alpha subunit; RNA binding S1 domain protein; SPTR: Translation initiation factor IF-2 subunit alpha; PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. (264 aa)    
Predicted Functional Partners:
eif2b
Translation initiation factor 2 subunit beta (aeIF-2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
 0.999
ADV65633.1
COGs: COG5257 Translation initiation factor 2 gamma subunit (eIF-2gamma; GTPase); InterPro IPR000795: IPR015256: IPR005225; KEGG: dka:DKAM_1347 translation initiation factor IF-2 subunit gamma; PFAM: protein synthesis factor GTP-binding; Initiation factor eIF2 gamma domain protein; SPTR: Translation initiation factor IF-2 subunit gamma; TIGRFAM: small GTP-binding protein; PFAM: Elongation factor Tu GTP binding domain; Initiation factor eIF2 gamma, C terminal; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU; translation initiation factor 2 subunit gamma.
  
 0.999
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR001593: IPR018281; KEGG: dka:DKAM_1335 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.998
rps4e
COGs: COG1471 Ribosomal protein S4E; InterProIPR000289: IPR000876: IPR013843: IPR002942: IPR 013845; KEGG: dka:DKAM_1163 30S ribosomal protein S4e; PFAM: Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4e; PFAM: S4 domain; Ribosomal family S4e; RS4NT (NUC023) domain; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 0.997
ADV64430.1
KEGG: dka:DKAM_0962 30S ribosomal protein S25e; SPTR: 30S ribosomal protein S25e.
   
 0.996
rps8
SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
 0.996
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.996
eif1a
Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
 0.995
rps17
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 0.995
rps19p
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 0.995
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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