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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64382.1HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR006402: IPR006439: IPR005834; KEGG: dka:DKAM_1013 HAD-superfamily hydrolase, subfamily IA; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, v [...] (230 aa)    
Predicted Functional Partners:
ADV64381.1
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.988
ADV64566.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: dka:DKAM_0032 phosphatases-like protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatases-like protein.
  
 
 0.929
rbcL
Ribulose 1,5-bisphosphate carboxylase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
    
 0.922
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
  
  
 0.601
ADV64373.1
COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017900: IPR017896; KEGG: dka:DKAM_1022 hydrogenase 4 Fe-S subunit; SPTR: Hydrogenase 4 Fe-S subunit; PFAM: 4Fe-4S binding domain.
  
  
 0.594
ADV64379.1
4Fe-4S ferredoxin, iron-sulfur binding domain protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900: IPR017896; KEGG: dka:DKAM_1016 4Fe-4S ferredoxin, iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
       0.564
ADV64374.1
NADH-ubiquinone oxidoreductase chain 49kDa; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268: IPR014029: IPR001501: IPR001135; KEGG: dka:DKAM_1021 NADH dehydrogenase (ubiquinone), 30 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; nickel-dependent hydrogenase large subunit; SPTR: NADH dehydrogenase (Ubiquinone), 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
  
    0.545
ADV64380.1
Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000103; KEGG: dka:DKAM_1015 putative glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative glutamate synthase subunit beta; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
       0.538
ADV64378.1
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: dka:DKAM_1017 NADH/ubiquinone/plastoquinone (complex I); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH/ubiquinone/plastoquinone (Complex I); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
       0.537
ADV64372.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: dka:DKAM_1023 NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
       0.536
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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