Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADV64415.1Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR018303: IPR006121: IPR006416: IPR001757: IPR 008250: IPR005834; KEGG: tag:Tagg_1238 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type [...] (791 aa)    
Predicted Functional Partners:
ADV64416.1
YHS domain-containing protein; COGs: COG3350 conserved hypothetical protein; InterPro IPR011017: IPR007029; KEGG: pas:Pars_1206 YHS domain-containing protein; PFAM: YHS domain-containing protein; SMART: TRASH domain-containing protein; SPTR: YHS domain protein; PFAM: YHS domain.
     
 0.841
ADV65223.1
Transcription regulator AsnC-type; InterPro IPR000485: IPR019888; KEGG: dka:DKAM_0906 putative transcriptional regulator, AsnC family; SMART: Transcription regulator AsnC-type; SPTR: Putative transcriptional regulator, AsnC family.
     
 0.829
ADV65301.1
CRISPR locus-related DNA-binding protein; InterPro IPR010163: IPR013383: IPR000835: IPR001845; KEGG: pcl:Pcal_0266 CRISPR-associated Csa3 family protein; PFAM: regulatory protein MarR; SMART: regulatory protein ArsR; SPTR: CRISPR-associated HTH regulatory protein, Csa3 family; TIGRFAM: CRISPR locus-related DNA-binding protein; CRISPR-associated protein DxTHG motif; PFAM: Sugar-specific transcriptional regulator TrmB; TIGRFAM: CRISPR locus-related DNA-binding protein.
  
  
 0.718
ADV64536.1
Phosphate ABC transporter ATP-binding protein, PhoT family; COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: dka:DKAM_0064 phosphate import ATP-binding protein PstB; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Phosphate import ATP-binding protein pstB; PFAM: ABC transporter.
     
 0.669
ADV64647.1
COGs: COG0306 Phosphate/sulphate permease; InterPro IPR001204; KEGG: dka:DKAM_0588 phosphate transporter; PFAM: phosphate transporter; SPTR: Phosphate transporter; PFAM: Phosphate transporter family.
  
  
 0.598
ADV64531.1
Small GTP-binding protein; COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225: IPR006073: IPR002917: IPR011619: IPR 011642; KEGG: dka:DKAM_0070 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain-containing protein; nucleoside recognition domain protein; SPTR: Ferrous iron transport protein B; TIGRFAM: small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain.
  
 
 0.589
ADV64476.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR018303: IPR001757: IPR000695: IPR004014: IPR 008250: IPR005834; KEGG: dka:DKAM_1201 H+-transporting ATPase related protein; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: H+-transporting ATPase related protein; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRF [...]
 
 
0.576
ADV64984.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027: IPR004099: IPR000815; KEGG: dka:DKAM_0296 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
     
 0.524
ADV64665.1
1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.499
ADV65271.1
COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR005950; KEGG: dka:DKAM_0217 molybdenum ABC transporter, periplasmic molybdate-binding protein; SPTR: Molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein.
     
 0.487
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.