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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64446.1KEGG: dka:DKAM_0923 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Gar1/Naf1 RNA binding region. (87 aa)    
Predicted Functional Partners:
nop10
RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
   
 0.999
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.969
ADV64445.1
Transcription factor TFIIB cyclin-related protein; COGs: COG1405 Transcription initiation factor TFIIIB Brf1 subunit/Transcription initiation factor TFIIB; InterPro IPR013137: IPR006670: IPR000812: IPR013150; KEGG: dka:DKAM_0922 transcription initiation factor TFIIIB; PFAM: Transcription factor TFIIB cyclin-related; SPTR: Transcription initiation factor TFIIIB; PFAM: TFIIB zinc-binding; Transcription factor TFIIB repeat.
  
  
 0.900
ADV65170.1
COGs: COG1498 Protein implicated in ribosomal biogenesis Nop56p homolog; InterPro IPR012976: IPR002687; KEGG: dka:DKAM_0815 C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; SPTR: Pre-mRNA processing ribonucleoprotein, binding region; PFAM: Putative snoRNA binding domain; NOSIC (NUC001) domain.
  
 
 0.847
ADV65479.1
Protein of unknown function DUF171; COGs: COG2106 conserved hypothetical protein; InterPro IPR003750; KEGG: dka:DKAM_1178 DUF171 domain containing protein; PFAM: protein of unknown function DUF171; SPTR: DUF171 domain containing protein; PFAM: Uncharacterized ACR, COG2106.
   
   0.729
ADV64644.1
KEGG: dka:DKAM_0585 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0113).
  
 
 0.709
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
  
  
 0.708
rps8e
COGs: COG2007 Ribosomal protein S8E; InterPro IPR018283: IPR020919: IPR001047; KEGG: dka:DKAM_0926 30S ribosomal protein S8e; SPTR: 30S ribosomal protein S8e; TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8e; TIGRFAM: ribosomal protein S8.e.
  
    0.687
ADV65566.1
Small GTP-binding protein; COGs: COG1084 GTPase; InterPro IPR002917: IPR006073: IPR005225; KEGG: dka:DKAM_1284 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
  
 
 0.672
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
   0.663
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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