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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64470.1Small GTP-binding protein; COGs: COG1163 GTPase; InterPro IPR005225: IPR006073: IPR002917: IPR004095; KEGG: dka:DKAM_0015 GTP-binding protein; PFAM: TGS domain-containing protein; GTP-binding protein HSR1-related; SPTR: GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TGS domain; TIGRFAM: small GTP-binding protein domain. (386 aa)    
Predicted Functional Partners:
ADV64469.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.879
rpl2
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.805
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
   0.792
rpl10
LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.772
rpl18
LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
   0.769
rpl30
LSU ribosomal protein L30P; InterPro IPR005997: IPR000517; KEGG: dka:DKAM_1154 50S ribosomal protein L30P; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30P; TIGRFAM: ribosomal protein L30P; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: 50S ribosomal protein L30P, archaeal.
   
   0.760
rps6e
COGs: COG2125 Ribosomal protein S6E (S10); InterPro IPR001377: IPR018282; KEGG: dka:DKAM_1348 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; SPTR: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
   
   0.749
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR001593: IPR018281; KEGG: dka:DKAM_1335 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
  
   0.747
rpl22
LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
   0.741
rpl23
LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
   0.740
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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